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Eminent heart surgeon Sir Magdi Yacoub, 71, has performed more transplants than anybody else in the world - saving thousands of lives across the globe.


No high street is complete without a charity shop. But such a phenomenon could never have been achieved had it not been for the energy and enterprise of one man.


Thousands of people's lives have been changed all across the world thanks to the awareness and generosity of Richard Carr-Gomm.


Serial killers and rapists have been caught and convicted, the innocent freed, and families reunited - thanks to the ground-breaking work of Sir Alec Jeffreys.


If it hadn't been for Sir Nicholas Winton, 669 children would almost certainly have perished in Nazi death camps.


President Bill Clinton called it the "most wondrous map ever produced by mankind". Others have compared the mapping of the human genome to the discovery of fire or the invention of the wheel.


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