Nobel Prize winner Peter Mansfield has saved millions of lives with his invention. Sir Peter, 75, failed his 11-plus and left school at 15 with no qualifications.
Thirty years ago, Lesley Brown made headlines when she gave birth to her daughter Louise, the world's first test tube baby.
Eminent heart surgeon Sir Magdi Yacoub, 71, has performed more transplants than anybody else in the world - saving thousands of lives across the globe.
No high street is complete without a charity shop. But such a phenomenon could never have been achieved had it not been for the energy and enterprise of one man.
Thousands of people's lives have been changed all across the world thanks to the awareness and generosity of Richard Carr-Gomm.
Serial killers and rapists have been caught and convicted, the innocent freed, and families reunited - thanks to the ground-breaking work of Sir Alec Jeffreys.
The Mirror's Pride of Britain Awards in partnership with TSB celebrate the achievements of truly remarkable people who make our world a better place.
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