To battle against cancer at any age is horrendous - but to survive it, suffer the heartbreak of losing a best friend and yet still think of others at Katy Miles's tender years defies belief.
Eight-year-old Hope Farrelly became Britain's youngest midwife when she delivered her baby brother at home. Little Hope was fast asleep in bed when she heard her mum, Melissa, screaming her name in the middle of the night.
Last summer, Shae Thomas was fighting for her life in intensive care. Astonishingly, less than a year on, the seven-year-old has shown extraordinary courage and managed to return to school with her friends.